Pick Your Scenic Drive Scenic Drives Name of Drive Description Highlights Where It Begins and Ends Length In Miles Website Great River Road Scenic drive along mighty Mississippi River Mark Twain boyhood homeGateway ArchSt Genevieve welcome centerNew Madrid historical museumAugust Busch conservation area Canton to Caruthersville 333 800/810-5200 Click here Lewis and Clark National Historic Trail Historic drive following Missouri River Daniel Boone homewineries in HermannAugust Busch conservation area St Charles to Jefferson City 120 402/661-1804 Click here Glade Top Trail weaving gravel road follows narrow ridge above rolling countryside great views near Ava 23 573/364-4621 Click here St Louis to Branson follow Missouri River to Jefferson City then through Ozark Mountains and Lake of the Ozarks to branson Capital in Jefferson CityLake of the OzarksBranson St Louis (from 94 Hwy) to Branson 275 800/916-8938 Click here Little Dixie Highway byway winds along Mississippi River with limestone bluffs providing stunning views victorian era streetscapesplantation era mansions Dupont Conservation Area east of New London to Clarksville 30 573/242-3993 Click here Crowley’s Ridge Parkway(on Route 25) thickly forested parks and interesting land formation victorian era streetscapesplantation era mansions Malden to Kennett 14 573/276-4519 or 573/448-3110 Click here Missouri Ozarks(on Route 19) beautiful rolling hills and scenic riverways Mark Twain National ForestOzark National Scenic Riverways Steelville to Thayer 310 800/877-1234 Click here Ozarks Run Scenic Byway beautiful rolling hills and great fall colors Taum Sauk Mountain State ParkElephant Rocks State Park starts at Washington State Park north of Potosi to Lesterville 78 314/540-1533 Click here Missouri Valley Road (on Route 21) beautiful Arcadia Valley Washington State ParkSt Francis MountainsPilot Knob State Historic Site starts at Route 21 in Affton to Doniphon near Arkansas line 188 800/916-8938 Click here Hermann Wine Trail historic wine district beautiful Hermann hilly river scenery New Florence through Hermann to New Haven 30 573/486-2323 Click here